STI Expert Hour Webinar: Why the Dose Matters: PrEP Strategies for HIV

January 11, 2022

Presented by Katherine Yang, PharmD, MPH

Pre-Exposure prophylaxis (PrEP) has been shown to be safe and effective in reducing HIV infection. With recent updates in PrEP, many options are available, and selection of the best regimen is the key to success. The purpose of this webinar is to review the pharmacologic basis for drug dosing and outline gaps and challenges in management.

Learning objectives

  1. Review the key pharmacokinetic and pharmacodynamic properties of emtricitabine/tenofovir disoproxil fumarate, emtricitabine/tenofovir alafenamide, and cabotegravir.
  2. Identify patients who may be appropriate for Daily vs. Event-Driven PrEP.
  3. Review key side effects of PrEP and potential strategies for management.
  4. Describe the role of adherence on PrEP effectiveness.

2021 PrEP Clinical Practice Guideline – Clinical Providers’ Supplement

Updated Clinical Providers’ Supplement accompanying the 2021 PrEP Clinical Practice Guideline.

Updates for 2021 include:

  • Checklist updated to include Descovy, 2-1-1 Truvada for MSM, and cabotegravir
  • Added PrEP with intramuscular cabotegravir (CAB) injections (conditional on FDA approval) recommendation for HIV prevention in adults 
  • Added information about Descovy and cabotegravir to Patient Information Sheets
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2021 PrEP Clinical Practice Guideline

Comprehensive information for the use of antiretroviral preexposure prophylaxis (PrEP) to prevent acquiring HIV infection.

Updates for 2021 include:

  • A recommendation to inform all sexually active adults and adolescents about PrEP
  • PrEP with intramuscular cabotegravir (CAB) injections (conditional on FDA approval) is recommended for HIV prevention in adults reporting sexual behaviors that place them at substantial ongoing risk of HIV exposure and acquisition.

Also view the updated PrEP Providers Supplement for 2021.

Comprehensive information for the use of antiretroviral preexposure prophylaxis (PrEP) to prevent acquiring HIV infection.

Updates for 2021 include:

  • A recommendation to inform all sexually active adults and adolescents about PrEP
  • PrEP with intramuscular cabotegravir (CAB) injections (conditional on FDA approval) is recommended for HIV prevention in adults reporting sexual behaviors that place them at substantial ongoing risk of HIV exposure and acquisition.

Also view the updated PrEP Providers Supplement for 2021.

Perinatal HIV and Congenital Syphilis—Dear Colleague Letter from CDPH

November 16, 2021: CDPH is asking for assistance in responding to concerning increases in congenital syphilis and perinatal HIV in California. Perinatal HIV transmission and congenital syphilis can be prevented with timely testing and treatment. A common risk factor, however, is receiving late or no prenatal care.

CDPH requests your assistance to implement the following policies and best practices to Screen, Treat and Prevent, and Prepare for perinatal transmissions

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PrEP Provider Pocket Card

Clinical PrEP essentials and key messages available in an easily accessible pocket card. From SF CBA and the San Francisco Health Network. 

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Social Determinants of Health and HIV

An understanding of social determinants is essential to the implementation of effective HIV treatment or prevention interventions. This engaging and informative one-hour online course, based on our popular two-day instructor-led training, provides an introduction to social determinants and HIV.

Learn more and register

Coming Together for Sexual Health

Coming Together for Sexual Health is a podcast for providers and advocates passionate about health equity and inclusive care. We unpack both the how and the why of improving sexual and reproductive health. From root structural problems to improvements in clinical care, we keep the attention on people most impacted by STIs, HIV, and emerging infectious diseases.

We are powered by leading sexual health trainers at UCSF’s California Prevention Training Center. Join our sex-positive conversations with expert clinicians, public health leaders, and community members wherever you get your podcasts.

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Podcast Episode

Beyond Birth: Midwives’ Role in Sexual Health
Dr. Bethany Golden, a nurse midwife, shares the many ways midwives support sexual and reproductive health beyond childbirth. Bethany shares how midwives provide holistic, patient-centered care, including contraception, STI treatment,…

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Vagina Obscura: A Conversation with Rachel E. Gross
Meet Rachel E. Gross, science journalist and author of Vagina Obscura: An Anatomical Voyage. In this first part of a two–part conversation, Rachel shares how her personal experience with bacterial vaginosis inspired…

STD/HIV Partner Services Interview Demonstration

This video provides an example of a mock partner services interview with a syphilis client. HIV prevention is also addressed extensively during the interview.

Learn more and register

Partner Services

CDC Train’s Passport to Partner Services online modules are for providers who conduct all aspects of Partner Services (PS), and they are designed for PS professionals of all experience levels.

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Integrating PrEP into Partner Services

CDC Train’s Integrating PrEP into Partner Services course is designed to give Disease Intervention Specialists (DIS) the tools they need to offer HIV pre-exposure prophylaxis (PrEP) to their clients by reviewing what PrEP is, how it differs from post-exposure prophylaxis (PEP) and how to assess whether a patient is eligible.

Learn more and register