2021 PrEP Clinical Practice Guideline – Clinical Providers’ Supplement

Updated Clinical Providers’ Supplement accompanying the 2021 PrEP Clinical Practice Guideline.

Updates for 2021 include:

Checklist updated to include Descovy, 2-1-1 Truvada for MSM, and cabotegravir
Added PrEP with intramuscular cabotegravir (CAB) injections (conditional on FDA approval) recommendation for HIV prevention in adults
Added information about Descovy and cabotegravir to Patient Information Sheets

2021 PrEP Clinical Practice Guideline

Comprehensive information for the use of antiretroviral preexposure prophylaxis (PrEP) to prevent acquiring HIV infection.

Updates for 2021 include:

A recommendation to inform all sexually active adults and adolescents about PrEP
PrEP with intramuscular cabotegravir (CAB) injections (conditional on FDA approval) is recommended for HIV prevention in adults reporting sexual behaviors that place them at substantial ongoing risk of HIV exposure and acquisition.

Also view the updated PrEP Providers Supplement for 2021.

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Comprehensive information for the use of antiretroviral preexposure prophylaxis (PrEP) to prevent acquiring HIV infection.

Updates for 2021 include:

A recommendation to inform all sexually active adults and adolescents about PrEP
PrEP with intramuscular cabotegravir (CAB) injections (conditional on FDA approval) is recommended for HIV prevention in adults reporting sexual behaviors that place them at substantial ongoing risk of HIV exposure and acquisition.

Also view the updated PrEP Providers Supplement for 2021.

California STI Treatment Guidelines Table for Adults and Adolescents—2021

These guidelines reflect the 2021 CDC STI Treatment Guidelines for adults and adolescents who are HIV negative as well as those with HIV.

View the online version of the guidelines

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Perinatal HIV and Congenital Syphilis—Dear Colleague Letter from CDPH

November 16, 2021: CDPH is asking for assistance in responding to concerning increases in congenital syphilis and perinatal HIV in California. Perinatal HIV transmission and congenital syphilis can be prevented with timely testing and treatment. A common risk factor, however, is receiving late or no prenatal care.

CDPH requests your assistance to implement the following policies and best practices to Screen, Treat and Prevent, and Prepare for perinatal transmissions

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PrEP Provider Pocket Card

Clinical PrEP essentials and key messages available in an easily accessible pocket card. From SF CBA and the San Francisco Health Network.

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2021 STI Treatment Guidelines

Current evidence-based prevention, diagnostic and treatment recommendations that replace the 2015 STI treatment guidance. Although the guidelines emphasize treatment, prevention strategies and diagnostic recommendations also are discussed.

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Syphilis Health Check™

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California Clinical Guidelines for Gonorrhea Treatment and Management of Suspected Treatment Failure

This guideline summarizes the California Department of Public Health (CDPH) clinical recommendations to enhance detection and management of suspected gonorrhea treatment failure and assure adequate treatment.

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Gonorrhea 2020 CDC Treatment Update

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Disseminated Gonococcal Infection in CA—Dear Colleague letter from CDPH

December 23, 2020: CDPH requests medical providers should reinstate routine screening recommendations for STDs in females <25 years of age, pregnant females, men who have sex with men and individuals with HIV. Providers should increase their clinical suspicion for DGI in patients with joint pain and undertake the following additional actions.

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