How to Prepare Bicillin® L-A with Lidocaine for Pain Control During Treatment for Syphilis

Developed in collaboration with Kristin Harter, PharmD, at the University of California, San Francisco, this instructional video provides step-by-step guidance for adding lidocaine to Bicillin® L-A for the mitigation of pain during treatment of syphilis. The California Department of Public Health (CDPH) also published a Protocol for Adding Lidocaine to Bicillin® L-A for Pain Management During Syphilis Treatment, which provides written step-by-step guidance for compounding and administering the two medications together. Clinicians can use it alongside this video for detailed preparation instructions. These resources are intended for healthcare professionals who provide clinical care and are involved in the preparation and administration of these medications.

Additional resources are available from our partners at the Saint Louis STI/HIV Prevention Training Center including a visual guide and printable brochure.