National STD Curriculum

A free educational website from the University of Washington STD Prevention Training Center.

Syphilis Treatment Intervals in Non-Pregnant Patients: A Clinical Resource for Providers

What are appropriate treatment intervals for late latent syphilis or syphilis of unknown duration in non-pregnant people?

Prepared by the STD Control Branch, California Department of Public Health and California Prevention Training Center. Revised February 2023.

STI Clinical Update Webinar-Back to Basics: Fundamentals of STI/HIV Prevention

Tuesday, March 28, 2023 from 12:00-1:15PM (PDT)
A review of screening, treatment, and vaccination tools to prevent STIs and HIV.
Presented by Drs. Caterina Liu and Kurtis Mohr

Learning Objectives:

  • Review screening and treatment guidance for STIs and HIV.
  • Integrate biochemical prevention tools for STIs and HIV into clinical practice.
  • Summarize recommendations for Hepatitis A, Hepatitis B, HPV, meningitis, and mpox vaccination.

STI Expert Hour Webinar: Mycoplasma Genitalium – What’s New?

January 18, 2023, 11:30 AM-12:45 PM (PST)

Presented by Dr. Lindley Barbee

This webinar will focus on an update of the clinical and epidemiologic aspects of Mycoplasma genitalium.

Learning Objectives:

  • Describe clinical syndromes associated with Mycoplasma genitalium
  • Recognize trends in M. genitalium antimicrobial resistance
  • Manage difficult treatment issues M. genitalium

California STI Screening Recommendations

California Sexually Transmitted Infections (STI) Screening Recommendations

This resource from the California Department of Public Health and California Prevention Training Center provides a concise, gender-specific summary of recommended STI screening practices.

Download the California STI Screening Recommendations.

Or view the recommendations as a website.

STI Clinical Update Webinar: Syndromic Management of STIs – Part 2

Tuesday, December 6, 2022 from 12:00PM-1:15PM (PST)

Presented by Drs. Kathleen Jacobson and Kelly Johnson

A case-based approach to recognizing sexually transmitted infections, with a focus on those that disseminate outside the genital tract.

Learning Objectives

  • Identify various presentations of STI ulcerative disease
  • Understand that certain sexually transmitted infections (STIs) can disseminate outside the genital tract, sometimes causing severe disease
  • Recognize the varied clinical manifestations of disseminated STIs (including disseminated gonococcal infections, secondary syphilis, and mpox)
  • Understand how to diagnose and manage disseminated STIs

Syndromic Management of STIs-Part 1

October 18, 2022

Presented by Drs. Rosalyn Plotzker, Akanksha Vaidya, and Eric Tang

The California Department of Public Health (CDPH) continues to see statewide increases in all reportable sexually transmitted infections (STIs), including syphilis, gonorrhea and chlamydia.

For many patients, these STIs manifest as a complex syndrome that involves local and systemic symptoms. This webinar is the first of a two-part series, featuring Drs. Rosalyn Plotzker,

Akanksha Vaidya, and Eric Tang of the CDPH Sexually Transmitted Diseases Control Branch who will lead a case-based discussion on the presentation, diagnosis and syndromic management of STIs.

Learning Objectives

  • Describe the differential diagnosis and management of patients with vaginal discharge and pelvic pain
  • Discuss the exam findings and treatment of patients with penile discharge and testicular pain
  • Explain the management of patients with anorectal pain in the setting of a known STI exposure

Clinical Interpretation of Syphilis Screening Algorithms

Clinical Interpretation of Syphilis Screening Algorithms

Providing guidance on the traditional screening algorithm and reverse screening algorithm. A resource for Local Health Jurisdictions.

various microscopic images of pathogens

Expedited Partner Therapy (EPT) for Sexually Transmitted Infections: A Resource for California Health Care Providers

Expedited Partner Therapy (EPT) for Sexually Transmitted Infections: A Resource for California Health Care Providers

Expedited Partner Therapy (EPT) is the clinical practice of treating sex partners of patients diagnosed with treatable sexually transmitted infections (STIs) – including chlamydia, gonorrhea, and trichomoniasis – without the health care provider first examining the partner(s).

This document explains what EPT is and why clinicians in California should prescribe it. In-depth references are also provided.

California Department of Public Health Logo

Clinical Practice Alert: Syphilis Screening, Diagnosis, and Treatment

Clinical Practice Alert: Syphilis Screening, Diagnosis, and Treatment

Rates of syphilis have been rising in the US, including in California, which has resulted in a corresponding rise in the rates of congenital syphilis (CS). Fifteen percent of women of childbearing age diagnosed with syphilis are pregnant.

These trends mirror a sharp increase in all stages of syphilis among females, which increased more than 500 percent during the same period. Download the PDF to learn more.

This Clinical Practice Alert includes management of primary, secondary, and latent syphilis. It does not include screening and management of syphilis in people who are pregnant or the diagnosis and treatment of tertiary syphilis.

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